NUF2 antibody

Product Specifications

Background

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:12438418, PubMed:14654001, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:17535814) . Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592) . The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020) .

Synonyms

Kinetochore protein Nuf2 (hNuf2, hNuf2R, hsNuf2) |Cell division cycle-associated protein 1|NUF2|CDCA1|NUF2R

Gene ID

83540

UniProt

Q9BZD4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

NUF2, NDC80 kinetochore complex component, homolog

Target

NUF2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IP

Field of Research

Cell Division and Proliferation

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

50 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IP

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

abx881358-01 5 nmol

Human hsa-miR-4529-3p miRNA Agomir

Ask

View Details

abx881358-02 10 nmol

Human hsa-miR-4529-3p miRNA Agomir

Ask

View Details

123241-ML750 100 µL

ALLC (Allantoate Amidinohydrolase, Probable Allantoicase) (MaxLight 750) discontinued

Ask

View Details

NBP2-72925JF549 0.1 mL

Mouse Monoclonal Necdin Antibody (OTI5D1) [Janelia Fluor 549]

Ask

View Details

L4502-10-HRP 200 µL

LRRK1, CT (Leucine-rich Repeat Kinase 1, Leucine-rich Repeat Serine/threonine-protein Kinase 1, FLJ23119, FLJ27465, KIAA1790, RIPK6, Roco1) (Azide free) (HRP) discontinued

Ask

View Details

43812176 3x 5 nmol

Sirt7 siRNA Oligos set (Rat)

Ask

View Details