NUDT21 antibody
Product Specifications
Background
Component of the cleavage factor Im(CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono-and di-adenosine nucleotides. May have a role in mRNA export.
Synonyms
Cleavage and polyadenylation specificity factor subunit 5|Cleavage and polyadenylation specificity factor 25 kDa subunit (CPSF 25 kDa subunit)|Cleavage factor Im complex 25 kDa subunit (CFIm25)|Nucleoside diphosphate-linked moiety X motif 21 (Nudix motif 21)|Nudix hydrolase 21|Pre-mRNA cleavage factor Im 68 kDa subunit|NUDT21|CFIM25|CPSF25|CPSF5
Gene ID
11051
UniProt
O43809
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
nudix(nucleoside diphosphate linked moiety X)-type motif 21
Target
NUDT21
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
26 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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