NUDT21 antibody

Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly (A) site cleavage and poly (A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono-and di-adenosine nucleotides. May have a role in mRNA export.

Cleavage and polyadenylation specificity factor subunit 5|Cleavage and polyadenylation specificity factor 25 kDa subunit (CPSF 25 kDa subunit) |Cleavage factor Im complex 25 kDa subunit (CFIm25) |Nucleoside diphosphate-linked moiety X motif 21 (Nudix motif 21) |Nudix hydrolase 21|Pre-mRNA cleavage factor Im 68 kDa subunit|NUDT21|CFIM25|CPSF25|CPSF5