5-Nitro BAPTA

5-Nitro BAPTA is a calcium chelator, combinded with 2-Me-substituted TM (as a fluorescent moiety), can be used to form a red fluorescent probe (CaTM-2 AM), for imaging of cytoplasmic Ca2+ in cultured living cells. 5-Nitro BAPTA is a building block used in the synthesis of Ca2+ specific chelators, Ca2+ buffers, and fluorescent Ca2+ indicators[1][2].

Product Specifications

CAS Number

[124251-83-8]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-nitro-bapta.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CN(C1=CC=CC=C1OCCOC2=CC([N+]([O-])=O)=CC=C2N(CC(O)=O)CC(O)=O)CC(O)=O

Molecular Formula

C22H23N3O12

Molecular Weight

521.43

References & Citations

[1]Takahiro Egawa, et al. Red Fluorescent Probe for Monitoring the Dynamics of Cytoplasmic Calcium Ions†. Angew Chem Int Ed. 2013, 52 (14) :3874-3877. |[2]Jones, et al. Purification and labeling of extracellular vesicles using a mixed mode resin composition: World Intellectual Property Organization, WO2019133842[P]. 2019-07-04.