NUAK2 antibody
Product Specifications
Background
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
Synonyms
NUAK family SNF1-like kinase 2|Omphalocele kinase 2|SNF1/AMP kinase-related kinase (SNARK)|NUAK2|OMPHK2|SNARK
Gene ID
81788
UniProt
Q9H093
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
NUAK family, SNF1-like kinase, 2
Target
NUAK2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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