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AI-10-47

AI-10-47 is a small molecule inhibitor of CBFβ-RUNX binding, with an IC50 of 3.2 μM[1].

Product Specifications

CAS Number

1256094-31-1

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

RUNX

Type

Reference compound

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ai-10-47.html

Concentration

10mM

Purity

98.93

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(F)(F)OC1=CC=C2N=C(C3=NC=CC=C3)NC2=C1

Molecular Formula

C13H8F3N3O

Molecular Weight

279.22

Precautions

H302, H315, H319, H335

References & Citations

[1]Anuradha Illendula, et al. Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers. EBioMedicine. 2016 Jun;8:117-131.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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