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NPC2 antibody

Product Specifications

Background

This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.

Synonyms

NPC intracellular cholesterol transporter 2|Epididymal secretory protein E1|Human epididymis-specific protein 1 (He1) |Niemann-Pick disease type C2 protein|NPC2|HE1

Gene ID

10577

UniProt

P61916

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Niemann-Pick disease, type C2

Target

NPC2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Cardiovascular, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

16 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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