NCF2 antibody
Product Specifications
Background
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms
Neutrophil cytosol factor 2 (NCF-2)|67 kDa neutrophil oxidase factor|NADPH oxidase activator 2|Neutrophil NADPH oxidase factor 2|p67-phox|NCF2|NOXA2|P67PHOX
Gene ID
4688
UniProt
P19878
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
neutrophil cytosolic factor 2
Target
NCF2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cancer, Metabolism, Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
68 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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