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NCF2 antibody

Product Specifications

Background

This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

Neutrophil cytosol factor 2 (NCF-2) |67 kDa neutrophil oxidase factor|NADPH oxidase activator 2|Neutrophil NADPH oxidase factor 2|p67-phox|NCF2|NOXA2|P67PHOX

Gene ID

4688

UniProt

P19878

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Neutrophil cytosolic factor 2

Target

NCF2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Cancer, Metabolism, Immunology

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

68 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

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