NOS1 antibody
Product Specifications
Background
NNOS belongs to the NOS family. NOS1 produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. NO is synthesized from L-arginine by nitric oxide synthases. NOS1 is a nitric oxide synthase which is highly expressed in skeletal muscle. Genetic variations in NOS1 gene are associated with susceptibility to infantile hypertrophic pyloric stenosis type 1 (IHPS1) .The antibody can recognize isoform 1,2,4,5 of NOS1.
Synonyms
Nitric oxide synthase 1|Constitutive NOS|NC-NOS|NOS type I|Neuronal NOS (N-NOS, nNOS) |Nitric oxide synthase, brain (bNOS) |Peptidyl-cysteine S-nitrosylase NOS1|NOS1
UniProt
P29475
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Nitric oxide synthase 1 (neuronal)
Target
NOS1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
161 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
101-301
Curated Selection
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