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NFATC2 antibody

Product Specifications

Background

Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.

Synonyms

Nuclear factor of activated T-cells, cytoplasmic 2 (NF-ATc2, NFATc2)|NFAT pre-existing subunit (NF-ATp)|T-cell transcription factor NFAT1|NFATC2|NFAT1|NFATP

Gene ID

4773

UniProt

Q13469

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

Target

NFATC2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IF, IHC

Field of Research

Immunology, Cardiovascular, Metabolism, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

135 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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