NENF antibody
Product Specifications
Background
Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity) . Plays a role in the human tumorigenesis (PubMed:22748190) .
Synonyms
Neudesin|Cell immortalization-related protein 2|Neuron-derived neurotrophic factor|Protein GIG47|Secreted protein of unknown function (SPUF protein) |NENF|CIR2|SPUF
Gene ID
29937
UniProt
Q9UMX5
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Neuron derived neurotrophic factor
Target
NENF
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, IHC, WB,IF
Field of Research
Neuroscience
Purification
Protein A+G purification
Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
18 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
7C8
Tested Applications
ELISA, IHC, WB, IF
Curated Selection
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