NELFB antibody
Product Specifications
Background
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding.
Synonyms
Negative elongation factor B (NELF-B)|Cofactor of BRCA1|NELFB|COBRA1|KIAA1182
Gene ID
25920
UniProt
Q8WX92
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
cofactor of BRCA1
Target
NELFB
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
66 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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