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NEK3 antibody

Product Specifications

Background

Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2.

Synonyms

Serine/threonine-protein kinase Nek3|HSPK 36|Never in mitosis A-related kinase 3 (NimA-related protein kinase 3) |NEK3

Gene ID

4752

UniProt

P51956

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

NIMA (never in mitosis gene a) -related kinase 3

Target

NEK3

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

52-60 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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