NCOR2 antibody
Product Specifications
Background
Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center(GC) reactions, mainly through the control of the GC B-cells proliferation and survival.
Synonyms
Nuclear receptor corepressor 2 (N-CoR2)|CTG repeat protein 26|SMAP270|Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT)|T3 receptor-associating factor (TRAC)|Thyroid-, retinoic-acid-receptor-associated corepressor|NCOR2|CTG26
Gene ID
9612
UniProt
Q9Y618
Host
Rabbit
Reactivity
Human
Immunogen
nuclear receptor co-repressor 2
Target
NCOR2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IF: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
180 kDa, 275 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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