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NCKIPSD antibody

Product Specifications

Background

Has an important role in stress fiber formation induced by active diaphanous protein homolog 1(DRF1). Induces microspike formation, in vivo(By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42(By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis.

Synonyms

NCK-interacting protein with SH3 domain|54 kDa VacA-interacting protein|54 kDa vimentin-interacting protein (VIP54)|90 kDa SH3 protein interacting with Nck|AF3p21|Dia-interacting protein 1 (DIP-1)|Diaphanous protein-interacting protein|SH3 adapter protein SPIN90|WASP-interacting SH3-domain protein (WISH)|Wiskott-Aldrich syndrome protein-interacting protein|NCKIPSD|AF3P21|SPIN90

Gene ID

51517

UniProt

Q9NZQ3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

NCK interacting protein with SH3 domain

Target

NCKIPSD

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP

Field of Research

Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

80 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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