NCKIPSD antibody
Product Specifications
Background
Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1) . Induces microspike formation, in vivo (By similarity) . In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42 (By similarity) . May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis.
Synonyms
NCK-interacting protein with SH3 domain|54 kDa VacA-interacting protein|54 kDa vimentin-interacting protein (VIP54) |90 kDa SH3 protein interacting with Nck|AF3p21|Dia-interacting protein 1 (DIP-1) |Diaphanous protein-interacting protein|SH3 adapter protein SPIN90|WASP-interacting SH3-domain protein (WISH) |Wiskott-Aldrich syndrome protein-interacting protein|NCKIPSD|AF3P21|SPIN90
Gene ID
51517
UniProt
Q9NZQ3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
NCK interacting protein with SH3 domain
Target
NCKIPSD
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
80 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
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