NCK2 antibody
Product Specifications
Background
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms
Cytoplasmic protein NCK2|Growth factor receptor-bound protein 4|NCK adaptor protein 2 (Nck-2) |SH2/SH3 adaptor protein NCK-beta|NCK2|GRB4
Gene ID
8440
UniProt
O43639
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
NCK adaptor protein 2
Target
NCK2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
43 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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