MYO16 antibody
Product Specifications
Background
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development. Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis(By similarity).
Synonyms
Unconventional myosin-XVI|Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3|Unconventional myosin-16|MYO16|KIAA0865|MYO16B|NYAP3
UniProt
Q9Y6X6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
myosin XVI
Target
MYO16
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
200-240 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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