PWWP3A antibody
Product Specifications
Background
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Synonyms
PWWP domain-containing DNA repair factor 3A (PWWP3A)|Mutated melanoma-associated antigen 1 (MUM-1)|PWWP domain-containing protein MUM1|Protein expandere|PWWP3A|EXPAND1|MUM1
Gene ID
84939
UniProt
Q2TAK8
Host
Rabbit
Reactivity
Human
Immunogen
melanoma associated antigen(mutated) 1
Target
PWWP3A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cancer, Immunology, Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70-80 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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