MUC16 antibody
Product Specifications
Background
MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators. The antibody recognizes the C-term of MUC16.
Synonyms
Mucin-16 (MUC-16) |Ovarian cancer-related tumor marker CA125 (CA-125) |Ovarian carcinoma antigen CA125|MUC16|CA125
Gene ID
94025
UniProt
Q8WXI7
Host
Rabbit
Reactivity
Human
Immunogen
Mucin 16, cell surface associated
Target
MUC16
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP,IHC
Field of Research
Cancer, Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
90-100 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP, IHC
Immunogen Sequence
Synthetic peptide derived from human CA125: 250-350aa
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