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MRAP antibody

Product Specifications

Background

Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R) . Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH) . May be involved in the intracellular trafficking pathways in adipocyte cells.

Synonyms

Melanocortin-2 receptor accessory protein|B27|Fat cell-specific low molecular weight protein|Fat tissue-specific low MW protein|MRAP|C21orf61|FALP

Gene ID

56246

UniProt

Q8TCY5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Melanocortin 2 receptor accessory protein

Target

MRAP

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Neuroscience, Signal Transduction, Immunology

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

12 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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