MRAP antibody
Product Specifications
Background
Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R) . Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH) . May be involved in the intracellular trafficking pathways in adipocyte cells.
Synonyms
Melanocortin-2 receptor accessory protein|B27|Fat cell-specific low molecular weight protein|Fat tissue-specific low MW protein|MRAP|C21orf61|FALP
Gene ID
56246
UniProt
Q8TCY5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Melanocortin 2 receptor accessory protein
Target
MRAP
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Signal Transduction, Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
12 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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