MRTFA antibody
Product Specifications
Background
Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation (By similarity) .
Synonyms
Myocardin-related transcription factor A (MRTF-A) |MKL/myocardin-like protein 1|Megakaryoblastic leukemia 1 protein|Megakaryocytic acute leukemia protein|MRTFA|KIAA1438|MAL|MKL1
Gene ID
57591
UniProt
Q969V6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Megakaryoblastic leukemia (translocation) 1
Target
MRTFA
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Stem Cells, Cardiovascular, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
145 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
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