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MRTFA antibody

Product Specifications

Background

Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation (By similarity) .

Synonyms

Myocardin-related transcription factor A (MRTF-A) |MKL/myocardin-like protein 1|Megakaryoblastic leukemia 1 protein|Megakaryocytic acute leukemia protein|MRTFA|KIAA1438|MAL|MKL1

Gene ID

57591

UniProt

Q969V6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Megakaryoblastic leukemia (translocation) 1

Target

MRTFA

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Stem Cells, Cardiovascular, Metabolism, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

145 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

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