RIOX2 antibody
Product Specifications
Background
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
Synonyms
Ribosomal oxygenase 2|60S ribosomal protein L27a histidine hydroxylase|Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA|Histone lysine demethylase MINA|MYC-induced nuclear antigen|Mineral dust-induced gene protein|Nucleolar protein 52|Ribosomal oxygenase MINA (ROX) |RIOX2|MDIG|MINA|MINA53|NO52
Gene ID
84864
UniProt
Q8IUF8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
MYC induced nuclear antigen
Target
RIOX2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
53 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
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