MEF2D antibody
Product Specifications
Background
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis(By similarity).The calculated molecular weight of MEF2D is 55 kDa, but Phosphorylated MEF2D is 60 kDa.
Synonyms
Myocyte-specific enhancer factor 2D|MEF2D
Gene ID
4209
UniProt
Q14814
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
myocyte enhancer factor 2D
Target
MEF2D
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Cardiovascular, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55-60 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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