MED4 antibody

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Mediator of RNA polymerase II transcription subunit 4|Activator-recruited cofactor 36 kDa component (ARC36) |Mediator complex subunit 4|TRAP/SMCC/PC2 subunit p36 subunit|Vitamin D3 receptor-interacting protein complex 36 kDa component (DRIP36) |MED4|ARC36|DRIP36|VDRIP