MED12 antibody
Product Specifications
Background
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.
Synonyms
Mediator of RNA polymerase II transcription subunit 12|Activator-recruited cofactor 240 kDa component (ARC240) |CAG repeat protein 45|Mediator complex subunit 12|OPA-containing protein|Thyroid hormone receptor-associated protein complex 230 kDa component (Trap230) |Trinucleotide repeat-containing gene 11 protein|MED12|ARC240|CAGH45|HOPA|KIAA0192|TNRC11|TRAP230
Gene ID
9968
UniProt
Q93074
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Mediator complex subunit 12
Target
MED12
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
230 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
