MCL1 antibody
Product Specifications
Background
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Synonyms
Induced myeloid leukemia cell differentiation protein Mcl-1|Bcl-2-like protein 3 (Bcl2-L-3) |Bcl-2-related protein EAT/mcl1|mcl1/EAT|MCL1|BCL2L3
Gene ID
4170
UniProt
Q07820
Host
Mouse
Reactivity
Human
Immunogen
Myeloid cell leukemia sequence 1 (BCL2-related)
Target
MCL1
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB, IF, IHC
Field of Research
Stem Cells, Cancer, Metabolism, Developmental biology
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:10000; IHC: 1:200-1:500; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
37 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
6F10
Tested Applications
ELISA, WB, IF, IHC
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