MCL1 antibody
Product Specifications
Background
This gene encodes an anti- apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
Synonyms
Induced myeloid leukemia cell differentiation protein Mcl-1|Bcl-2-like protein 3 (Bcl2-L-3) |Bcl-2-related protein EAT/mcl1|mcl1/EAT|MCL1|BCL2L3
Gene ID
4170
UniProt
Q07820
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Myeloid cell leukemia sequence 1 (BCL2-related)
Target
MCL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Stem Cells, Cancer, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:100 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
37 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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