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MBD4 antibody

Product Specifications

Background

Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.

Synonyms

Methyl-CpG-binding domain protein 4|Methyl-CpG-binding endonuclease 1|Methyl-CpG-binding protein MBD4|Mismatch-specific DNA N-glycosylase|MBD4|MED1

Gene ID

8930

UniProt

O95243

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Methyl-CpG binding domain protein 4

Target

MBD4

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Metabolism, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

66 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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