MAT1A antibody
Product Specifications
Background
This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.
Synonyms
S-adenosylmethionine synthase isoform type-1 (AdoMet synthase 1)|Methionine adenosyltransferase 1 (MAT 1)|Methionine adenosyltransferase I/III (MAT-I/III)|MAT1A|AMS1|MATA1
Gene ID
4143
UniProt
Q00266
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
methionine adenosyltransferase I, alpha
Target
MAT1A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
44 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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