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MAT1A antibody

Product Specifications

Background

This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.

Synonyms

S-adenosylmethionine synthase isoform type-1 (AdoMet synthase 1) |Methionine adenosyltransferase 1 (MAT 1) |Methionine adenosyltransferase I/III (MAT-I/III) |MAT1A|AMS1|MATA1

Gene ID

4143

UniProt

Q00266

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Methionine adenosyltransferase I, alpha

Target

MAT1A

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

44 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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