MAPK4 antibody
Product Specifications
Background
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity) .
Synonyms
Mitogen-activated protein kinase 4 (MAP kinase 4, MAPK 4) |Extracellular signal-regulated kinase 4 (ERK-4) |MAP kinase isoform p63 (p63-MAPK) |MAPK4|ERK4|PRKM4
Gene ID
5596
UniProt
P31152
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Mitogen-activated protein kinase 4
Target
MAPK4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
68 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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