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MAPK4 antibody

Product Specifications

Background

Atypical MAPK protein. Phosphorylates microtubule-associated protein 2(MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle(By similarity).

Synonyms

Mitogen-activated protein kinase 4 (MAP kinase 4, MAPK 4)|Extracellular signal-regulated kinase 4 (ERK-4)|MAP kinase isoform p63 (p63-MAPK)|MAPK4|ERK4|PRKM4

Gene ID

5596

UniProt

P31152

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

mitogen-activated protein kinase 4

Target

MAPK4

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Signal Transduction, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

68 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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