MAP1B antibody
Product Specifications
Background
Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity) . Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.
Synonyms
Microtubule-associated protein 1B (MAP-1B) |MAP1B heavy chain|MAP1 light chain LC1|MAP1B
Gene ID
4131
UniProt
P46821
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Microtubule-associated protein 1B
Target
MAP1B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, FC, IF
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
320 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, FC, IF
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