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MALT1 antibody

Product Specifications

Background

Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.

Synonyms

Mucosa-associated lymphoid tissue lymphoma translocation protein 1|MALT lymphoma-associated translocation|Paracaspase|MALT1|MLT

Gene ID

10892

UniProt

Q9UDY8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

mucosa associated lymphoid tissue lymphoma translocation gene 1

Target

MALT1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IHC, IF, WB, FC

Field of Research

Immunology, Signal Transduction, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

90 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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