MALT1 antibody
Product Specifications
Background
Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.
Synonyms
Mucosa-associated lymphoid tissue lymphoma translocation protein 1|MALT lymphoma-associated translocation|Paracaspase|MALT1|MLT
Gene ID
10892
UniProt
Q9UDY8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Mucosa associated lymphoid tissue lymphoma translocation gene 1
Target
MALT1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IF, WB, FC
Field of Research
Immunology, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
90 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, IF, WB, FC
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