MAGEC2 antibody
Product Specifications
Background
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes(E2) at the E3:substrate complex.
Synonyms
Melanoma-associated antigen C2|Cancer/testis antigen 10 (CT10)|Hepatocellular carcinoma-associated antigen 587|MAGE-C2 antigen|MAGE-E1 antigen|MAGEC2|HCA587|MAGEE1
Gene ID
51438
UniProt
Q9UBF1
Host
Rabbit
Reactivity
Human
Immunogen
melanoma antigen family C, 2
Target
MAGEC2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Cancer, Developmental biology
Purification
Immunogen affinity purified
Dilution
IHC: 1:20 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
41 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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