Biatractylolide

Biatractylolide is a compound isolated from the ethyl acetate extract of Atractylodes macrocephala. Biatractylolide has antitumor and antioxidant activities. Biatractylolide improves cell viability, inhibits the apoptosis of cells induced by glutamate, and reduces the activity of LDH. Biatractylolide has neuroprotective effects[1].

Product Specifications

CAS Number

[182426-37-5]

Product Name Alternative

(+) -Biatractylolide

UNSPSC

12352005

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/biatractylolide.html

Purity

99.39

Solubility

10 mM in DMSO

Smiles

CC1=C2[C@@](OC1=O)([C@]34C(C[C@@]5([H])[C@](C3)(CCCC5=C)C)=C(C(O4)=O)C)C[C@]6([C@](C(CCC6)=C)([H])C2)C

Molecular Formula

C30H38O4

Molecular Weight

462.62

References & Citations

[1]Zhu L, et al. Biatractylolide Modulates PI3K-Akt-GSK3β-Dependent Pathways to Protect against Glutamate-Induced Cell Damage in PC12 and SH-SY5Y Cells. Evid Based Complement Alternat Med.