MAD2L1 antibody
Product Specifications
Background
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
Synonyms
Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2)|Mitotic arrest deficient 2-like protein 1 (MAD2-like protein 1)|MAD2L1|MAD2
Gene ID
4085
UniProt
Q13257
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
MAD2 mitotic arrest deficient-like 1(yeast)
Target
MAD2L1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
25-30 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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