LRRC8C antibody
Product Specifications
Background
Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E) ; channel characteristics depend on the precise subunit composition.
Synonyms
Volume-regulated anion channel subunit LRRC8C|Factor for adipocyte differentiation 158|Leucine-rich repeat-containing protein 8C|LRRC8C|AD158|FAD158
Gene ID
84230
UniProt
Q8TDW0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Leucine rich repeat containing 8 family, member C
Target
LRRC8C
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IF, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IF, IHC
Curated Selection
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