LPCAT1 antibody
Product Specifications
Background
Possesses both acyltransferase and acetyltransferase activities(PubMed:16864775, PubMed:21498505). Activity is calcium-independent(By similarity). Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine(LPC) into phosphatidylcholine(PC)(PubMed:21498505). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively(PubMed:16704971). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology(PubMed:16864775). Involved in the regulation of lipid droplet number and size(PubMed:25491198).
Synonyms
Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1, LPCAT-1, LysoPC acyltransferase 1)|1-acylglycerol-3-phosphate O-acyltransferase|1-acylglycerophosphocholine O-acyltransferase|1-alkenylglycerophosphocholine O-acyltransferase|1-alkylglycerophosphocholine O-acetyltransferase|Acetyl-CoA:lyso-platelet-activating factor acetyltransferase (Acetyl-CoA:lyso-PAF acetyltransferase, Lyso-PAF acetyltransferase, LysoPAFAT)|Acyltransferase-like 2|Phosphonoformate immuno-associated protein 3|LPCAT1|AYTL2|PFAAP3
Gene ID
79888
UniProt
Q8NF37
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
lysophosphatidylcholine acyltransferase 1
Target
LPCAT1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IF, WB, IP, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
59 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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