LPCAT1 antibody
Product Specifications
Background
Possesses both acyltransferase and acetyltransferase activities (PubMed:16864775, PubMed:21498505) . Activity is calcium-independent (By similarity) . Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC) (PubMed:21498505) . Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (PubMed:16704971) . May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (PubMed:16864775) . Involved in the regulation of lipid droplet number and size (PubMed:25491198) .
Synonyms
Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1, LPCAT-1, LysoPC acyltransferase 1) |1-acylglycerol-3-phosphate O-acyltransferase|1-acylglycerophosphocholine O-acyltransferase|1-alkenylglycerophosphocholine O-acyltransferase|1-alkylglycerophosphocholine O-acetyltransferase|Acetyl-CoA:lyso-platelet-activating factor acetyltransferase (Acetyl-CoA:lyso-PAF acetyltransferase, Lyso-PAF acetyltransferase, LysoPAFAT) |Acyltransferase-like 2|Phosphonoformate immuno-associated protein 3|LPCAT1|AYTL2|PFAAP3
Gene ID
79888
UniProt
Q8NF37
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Lysophosphatidylcholine acyltransferase 1
Target
LPCAT1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IF, WB, IP, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
59 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IF, WB, IP, IHC
Curated Selection
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