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LPCAT1 antibody

Product Specifications

Background

Possesses both acyltransferase and acetyltransferase activities (PubMed:16864775, PubMed:21498505) . Activity is calcium-independent (By similarity) . Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC) (PubMed:21498505) . Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (PubMed:16704971) . May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (PubMed:16864775) . Involved in the regulation of lipid droplet number and size (PubMed:25491198) .

Synonyms

Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1, LPCAT-1, LysoPC acyltransferase 1) |1-acylglycerol-3-phosphate O-acyltransferase|1-acylglycerophosphocholine O-acyltransferase|1-alkenylglycerophosphocholine O-acyltransferase|1-alkylglycerophosphocholine O-acetyltransferase|Acetyl-CoA:lyso-platelet-activating factor acetyltransferase (Acetyl-CoA:lyso-PAF acetyltransferase, Lyso-PAF acetyltransferase, LysoPAFAT) |Acyltransferase-like 2|Phosphonoformate immuno-associated protein 3|LPCAT1|AYTL2|PFAAP3

Gene ID

79888

UniProt

Q8NF37

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Lysophosphatidylcholine acyltransferase 1

Target

LPCAT1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IF, WB, IP, IHC

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

59 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, IF, WB, IP, IHC

Frequently Asked Questions

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