LNPEP antibody
Product Specifications
Background
Release of an N-terminal amino acid, cleaves before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain.
Synonyms
Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase)|Insulin-regulated membrane aminopeptidase|Insulin-responsive aminopeptidase (IRAP)|Oxytocinase (OTase)|Placental leucine aminopeptidase (P-LAP)|Leucyl-cystinyl aminopeptidase, pregnancy serum form|LNPEP|OTASE
Gene ID
4012
UniProt
Q9UIQ6
Host
Rabbit
Reactivity
Human
Immunogen
leucyl/cystinyl aminopeptidase
Target
LNPEP
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cardiovascular, Metabolism, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
117-125 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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