LAS1L antibody
Product Specifications
Background
Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP(5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Synonyms
Ribosomal biogenesis protein LAS1L|Endoribonuclease LAS1L|Protein LAS1 homolog|LAS1L
Gene ID
81887
UniProt
Q9Y4W2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
LAS1-like
Target
LAS1L
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
83 kDa, 70-75 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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