LARP1 antibody
Product Specifications
Background
RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex. Associates with the mRNA 5'cap in an MTOR-dependent manner and associates with mRNAs containing a 5' terminal oligopyrimidine (5'TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5'TOP, thereby regulating cell growth and proliferation. Positively regulates the replication of dengue virus (DENV) (PubMed:26735137) .
Synonyms
La-related protein 1|La ribonucleoprotein domain family member 1|LARP1|KIAA0731|LARP
Gene ID
23367
UniProt
Q6PKG0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
La ribonucleoprotein domain family, member 1
Target
LARP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140-150 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MR217352L3V 200 µL
Arhgap6 (NM_009707) Mouse Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details ![CDY2B Mouse Monoclonal Antibody [Clone 8H6]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
