KRT6B antibody
Product Specifications
Background
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita.
Synonyms
Keratin, type II cytoskeletal 6B|Cytokeratin-6B (CK-6B) |Keratin-6B (K6B) |Type-II keratin Kb10|KRT6B|K6B|KRTL1
Gene ID
3854
UniProt
P04259
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Keratin 6B
Target
KRT6B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:1000-1:5000; IHC: 1:50-1:500; IF: 1:200-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
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