KRAS antibody
Product Specifications
Background
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838) . Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306) .
Synonyms
GTPase KRas|K-Ras 2|Ki-Ras|c-K-ras|c-Ki-ras|GTPase KRas, N-terminally processed|KRAS|KRAS2|RASK2
Gene ID
3845
UniProt
P01116
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Target
KRAS
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP, IHC
Field of Research
Cancer, Immunology, Signal Transduction, Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:1000; IHC: 1:50 - 1:200; IP: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
21 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP, IHC
Immunogen Sequence
1-189aa
Curated Selection
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