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KLHL2 antibody

Product Specifications

Background

Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation (By similarity) . Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.

Synonyms

Kelch-like protein 2|Actin-binding protein Mayven|KLHL2

Gene ID

11275

UniProt

O95198

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Kelch-like 2, Mayven (Drosophila)

Target

KLHL2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Neuroscience

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

66 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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