Tebufenozide
Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells[1][2].
Product Specifications
CAS Number
[112410-23-8]
UNSPSC
12352005
Hazard Statement
H411
Target
Apoptosis; Insecticide; MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tebufenozide.html
Concentration
10mM
Purity
99.28
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(N(C(C)(C)C)NC(C1=CC=C(CC)C=C1)=O)C2=CC(C)=CC(C)=C2
Molecular Formula
C22H28N2O2
Molecular Weight
352.47
Precautions
H411
References & Citations
[1]Muhammad Fiaz, et al. Toxicological and Morphological Effects of Tebufenozide on Anticarsia Gemmatalis (Lepidoptera: Noctuidae) Larvae. Chemosphere. 2018 Dec;212:337-345.|[2]Xiaoqin Yu, et al. Cytotoxic Effects of Tebufenozide in Vitro Bioassays. Ecotoxicol Environ Saf. 2016 Jul;129:180-8.|[3]Xu W, et al. Tebufenozide induces G1/S cell cycle arrest and apoptosis in human cells. Environ Toxicol Pharmacol. 2017 Jan;49:89-96.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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