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KHSRP antibody

Product Specifications

Background

Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity) . Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE) . May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.

Synonyms

Far upstream element-binding protein 2 (FUSE-binding protein 2) |KH type-splicing regulatory protein (KSRP) |p75|KHSRP|FUBP2

Gene ID

8570

UniProt

Q92945

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

KH-type splicing regulatory protein

Target

KHSRP

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Epigenetics, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

75 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

Frequently Asked Questions

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